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From EurekAlert! - Breaking News:
Using a behavioral animal model, researchers of a new study, scheduled for publication in the August 1st issue of Biological Psychiatry, have found that the physical surroundings where alcohol cues are experienced can greatly influence the ability of those cues to trigger relapse.
Specifically, Chaudhri and colleagues taught rats to learn that a brief tone signaled when a small amount of alcohol would be available in a fluid receptacle for them to drink.
This learning occurred in a distinctive environment consisting of a particular appearance, smell, and lighting.
They were then put into a second, unique context with a different appearance, smell, and lighting, and were repeatedly exposed to the tone but never given alcohol.
If used in the clinic, this technique of extinguishing responses to alcohol cues in multiple contexts could greatly increase the efficacy of current behavioral treatments for alcoholism.
Additional research will clearly need to be undertaken to determine the effectiveness of such a technique, but these findings indicate that it may a promising addition to addiction therapies.
The authors are all affiliated with the Ernest Gallo Clinic and Research Center, University of California at San Francisco, Emeryville, California.
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Posted on July 29, 2008 10:09 PM
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