Human Services News

From EurekAlert! - Breaking News:

Researchers at the University of Chicago are studying possible connections between living in disadvantaged neighborhoods and the development of early onset breast cancer in a path-breaking project led by Sarah Gehlert, Director of the Center for Interdisciplinary Health Disparities Research.

As part of the work of the CIHDR, Olopade and other scholars studied early onset breast cases in Nigerian women, whose genetic heritage is similar to African-Americans because the ancestors of African Americans largely came from West Africa.

While white women usually develop the disease after menopause, it develops prior to menopause among women of African heritage.

Co-author Martha McClintock, the David Lee Shillinglaw Distinguished Service Professor in Psychology at the University, carried out the animal modeling by studying the development of spontaneous mammary tumors in socially isolated rats.

Researchers are studying 230 black women with newly diagnosed breast cancers living in predominantly black Chicago neighborhoods to learn about environmental factors, such asneighborhood features that might lead to social isolation.

"These women experience stress from dealing with situations they cannot control, from seeing crime in their neighborhood, from being afraid to go out, and not being able to form casual relationships with their neighbors that might make them feel safe," Gehlert said.

By studying multiple pathways to the development of the disease, leading from environmental challenges to gene regulation, the team will help inform policy makers about making decisions in how to create cost-effective interventions, McClintock said.

The team said that the women's vulnerability to stress and social isolation could be reduced if communities work with neighborhood and city leaders to reduce building vacancies and establish networks that would give women a greater feeling of control over their environments.

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