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Feature Story 
October 18, 2007
Effectiveness of Most PTSD Therapies is Uncertain

From EurekAlert! - Breaking News:

Many people, including significant proportions of active duty military personnel and veterans, suffer from post-traumatic stress disorder (PTSD), often in conjunction with other injuries or illnesses.

While several drugs and psychotherapies are used to treat PTSD, many of the studies concerning their effectiveness have problems; as a result, they do not provide a clear picture of what works and what doesn't, says a new report from the Institute of Medicine.

The committee reviewed 53 studies of pharmaceuticals and 37 studies of psychotherapies used in PTSD treatment and concluded that because of shortcomings in many of the studies, there is not enough reliable evidence to draw conclusions about the effectiveness of most treatments.

There are sufficient data to conclude that exposure therapies -- such as exposing individuals to a real or surrogate threat in a safe environment to help them overcome their fears -- are effective in treating people with PTSD.

Our findings underscore the urgent need for high-quality studies that can assist clinicians in providing the best possible care to veterans and others who suffer from this serious disorder."

Anticonvulsants, antidepressants -- including selective serotonin reuptake inhibitors (SSRIs) -- monoamine oxidase inhibitors (MAOIs), and novel antipsychotics such as olanzapine and risperidone are among the drugs used to treat these patients.

The committee emphasized that its role was solely to review what is known about the effectiveness of various PTSD treatments, and not to offer or suggest guidelines on what health care professionals or patients should do.

The National Academy of Sciences, National Academy of Engineering, Institute of Medicine, and National Research Council make up the National Academies.

Read more from this post.

Posted on October 18, 2007 6:40 PM


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